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Results

The data from the vitamin C study clearly shows that The Right C® has significantly better absorption compared to Another Vitamin C.

Figure 1 displays the total plasma AA concentration, correcting for baseline values, over time. A Two-Way Repeated Measures Analysis of Variance was performed. The results from the vitamin C study show that both the main effects of “Time” and “Type of C” were significant (p=0.0001 and p=0.0002, respectively). There was not a significant interaction effect.


Table 1 depicts the mean value for Another Vitamin C and The Right C® at each time point.

Average increase, above baseline, in total plasma AA (mg/L) at each time interval after ingestion of the test material

Time (Min) Another Vitamin C The Right C®
30 1.322 4.295
60 4.170 8.331
90 6.222 11.61


Following the Two-Way Repeated Measures Analysis of Variance,
t-test post-hoc analysis was performed comparing Another Vitamin C and The Right C® at each time interval.


diagrams1-4


Figure 2
shows the comparison between Another Vitamin C and The Right C® for increase in total plasma AA (mg/L) above baseline at 30 minutes. T-test post-hoc analysis shows that The Right C® had a significantly higher increase in total plasma AA above baseline compared to Another Vitamin C (p=0.0188).



Figure 3
shows the comparison between Another Vitamin C and The Right C® for increase in total plasma AA (mg/L) above baseline at 60 minutes. T-test post-hoc analysis shows that The Right C® had a significantly higher increase in total plasma AA above baseline compared to Another Vitamin C (p=0.0278).



Figure 4
shows the comparison between Another Vitamin C and The Right C® for increase in total plasma AA (mg/L) above baseline at 90 minutes. T-test post-hoc analysis shows that The Right C® had a significantly higher increase in total plasma AA above baseline compared to Another Vitamin C (p=0.0100).


Absorption rate was calculated and is graphically depicted in Figure 5. It was assumed that absorption would be linear over time, and linear regression supports this assumption (R2=0.50575). The absorption rate of The Right C®was 196% higher than the absorption rate of Another Vitamin C. Put another way, the absorption rate of Another Vitamin C was only 50.7% that of The Right C®. Assuming that the absorption rate of either source of ascorbic acid would continue to be linear over time, and that total absorption would be complete after 4 hours, the total amount of ascorbic acid delivered to the plasma from a 1000 mg dose of The Right C® would be 31.883 mg/L, compared to a 16.187 mg/L increase after a 1000 mg dose of Another Vitamin C. Calculating the area under the curve (AUC) of The Right C® and Another Vitamin C shows that the AUC of The Right C® is 205% higher than that of Another Vitamin C (488.6 units versus 238.3 units, respectively).


Discussion
The data indicates that The Right C® formulation is absorbed more rapidly than Another Vitamin C by 196%. Alternatively, Another Vitamin C is absorbed only 50.7% as quickly as The Right C®. The Right C® raises plasma AA levels more rapidly and higher than Another Vitamin C. Higher plasma levels promote more rapid increases in intracellular AA levels. Higher AA levels enable the cell to utilize AA at a higher rate in cell metabolism and provide superior anti-oxidant action in the plasma as well as in the cell. Thus, The Right C® provides superior anti-oxidant protection compared to Another Vitamin C.